HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → tert-Butyl (6-{[(2-chloropyridin-3-yl)sulfonyl]amino}-2-methoxypyridin-3-yl)methylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 2-Chloropyridine-3-sulfonyl chloride | HCID 10219968 | — |
| Reactant | Tert-butyl(6-amino-2-methoxypyridin-3-yl)methylcarbamate | HCID 131734695 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | tert-Butyl (6-{[(2-chloropyridin-3-yl)sulfonyl]amino}-2-methoxypyridin-3-yl)methylcarbamate | HCID 131734696 | 64.4% |
Reaction Steps
The title compound (1.51 g, 3.53 mmol) was prepared from 2-chloropyridine-3-sulfonyl chloride (1.16 g, 5.48 mmol), tert-butyl(6-amino-2-methoxypyridin-3-yl)methylcarbamate (IntC7) (1.53 g, 6.03 mmol) and pyridine (1.33 mL, 16.4 mmol) in DCM (20 mL) at rt using the methods of (IntC1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249160B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-0d992552196f4cac842a9ca7fbf09353 |
| Source note | uspto-grants-2016_02 |