HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → 2-Chloro-N-(6-methoxy-5-methylpyridin-2-yl)pyridine-3-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 2-Chloropyridine-3-sulfonyl chloride | HCID 10219968 | — |
| Reactant | 6-Methoxy-5-methylpyridin-2-amine | HCID 90022170 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 2-Chloro-N-(6-methoxy-5-methylpyridin-2-yl)pyridine-3-sulfonamide | HCID 90029758 | 79.8% |
Reaction Steps
The title compound (1.60 g, 5.10 mmol) was prepared from 2-chloropyridine-3-sulfonyl chloride (1.35 g, 6.39 mmol), 6-methoxy-5-methylpyridin-2-amine (IntC10) (970 mg, 7.02 mmol) and pyridine (1.55 mL, 19.2 mmol) in 1,4-dioxane (25 mL) at rt using the methods of (IntC1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249160B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-e1e3bf73c69247e3a45f250406760704 |
| Source note | uspto-grants-2016_02 |