HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → tert-Butyl(5-{[(2-chloropyridin-3-yl)sulfonyl]amino}-3-methylpyridin-2-yl)methylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 2-Chloropyridine-3-sulfonyl chloride | HCID 10219968 | — |
| Reactant | Tert-butyl(5-amino-3-methylpyridin-2-yl)methylcarbamate | HCID 131734698 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | tert-Butyl(5-{[(2-chloropyridin-3-yl)sulfonyl]amino}-3-methylpyridin-2-yl)methylcarbamate | HCID 131734697 | 111.8% |
Reaction Steps
The title compound (1.98 g) was prepared from 2-chloropyridine-3-sulfonyl chloride (910 mg, 4.29 mmol), tert-butyl(5-amino-3-methylpyridin-2-yl)methylcarbamate (IntC12) (1.12 g, 4.72 mmol) and pyridine (1.04 mL, 12.9 mmol) in DCM (25 mL) at rt using the methods of (IntC1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249160B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-8c03eb20a4734beba0cf4d631ea299fd |
| Source note | uspto-grants-2016_02 |