(3-Fluoropyridin-2-yl)methanol → HCID 72721482, compound

HRID 1772937Notes

Reaction equation

HRID 1772937 reaction equation
[F:1][C:2]1[C:3]([CH2:8]O)=[N:4][CH:5]=[CH:6][CH:7]=1.ClC1C=C(OC)C=C(F)C=1C[N:14]1[C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=2[S:17](=[O:25])(=[O:24])[N:16]([C:26]2[CH:31]=[CH:30][C:29]([O:32][CH3:33])=[C:28]([O:34][CH3:35])[CH:27]=2)[C:15]1=[O:36]>>[CH3:35][O:34][C:28]1[CH:27]=[C:26]([N:16]2[C:15](=[O:36])[N:14]([CH2:8][C:3]3[C:2]([F:1])=[CH:7][CH:6]=[CH:5][N:4]=3)[C:19]3[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=3[S:17]2(=[O:24])=[O:25])[CH:31]=[CH:30][C:29]=1[O:32][CH3:33]

Participants

3

Reactant 2

HCID 19703803(3-Fluoropyridin-2-yl)methanolHCID 72722084HCID 72722084, compound

Product 1

HCID 72721482HCID 72721482, compound

Procedure

The title compound (152 mg, 0.34 mmol) was prepared from (IntA1) (167 mg, 0.50 mmol), and (3-fluoropyridin-2-yl)methanol (95 mg, 0.75 mmol) using the methods of (113).

Sources & evidence

ORD record
ord-8c75dd5820ed4b868b8d1b1a4141e03b
Source dataset
uspto-grants-2016_02
Patent number
US09249160B2

Reaction notes

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