Cesium carbonate → HCID 90054934, compound

HRID 1772991Notes

Reaction equation

HRID 1772991 reaction equation
Br[CH2:2][C:3]1[CH:7]=[C:6]([CH3:8])[O:5][N:4]=1.C([O-])([O-])=O.[Cs+].[Cs+].[Cl:15][C:16]1[CH:42]=[CH:41][CH:40]=[C:39]([F:43])[C:17]=1[CH2:18][N:19]1[C:24]2[CH:25]=[CH:26][CH:27]=[CH:28][C:23]=2[S:22](=[O:30])(=[O:29])[N:21](CC2C=CC=CN=2)[C:20]1=[O:38]>>[Cl:15][C:16]1[CH:42]=[CH:41][CH:40]=[C:39]([F:43])[C:17]=1[CH2:18][N:19]1[C:24]2[CH:25]=[CH:26][CH:27]=[CH:28][C:23]=2[S:22](=[O:30])(=[O:29])[N:21]([CH2:2][C:3]2[CH:7]=[C:6]([CH3:8])[O:5][N:4]=2)[C:20]1=[O:38]

Participants

4

Reactant 3

HCID 10796Cesium carbonateHCID 27763043-(Bromomethyl)-5-methylisoxazoleHCID 90054655HCID 90054655, compound

Product 1

HCID 90054934HCID 90054934, compound

Procedure

The title compound (0.16 g, 0.37 mmol) was prepared from (IntE1) (0.3 g, 0.88 mmol), 3-(bromomethyl)-5-methyl-1,2-oxazole (0.11 g, 0.63 mmol) and Cs2CO3 (0.86 g, 2.64 mmol) using the methods of (128).

Sources & evidence

ORD record
ord-e8a90400b410483d92e6dd7aedfee4e9
Source dataset
uspto-grants-2016_02
Patent number
US09249160B2

Reaction notes

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