HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 72720780, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2,6-Difluoro-4-methoxybenzyl bromide | HCID 3354272 | — |
| Reactant | 2-(4-methoxy-3,5-dimethylphenyl)-4-(2,4,6-trifluorobenzyl)-2H-1,2,4-benzothiadiazin-3(4H)-one 1,1-dioxide | HCID 72722085 | — |
| Reactant | HCID 90054683 | HCID 90054683 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 72720780 | HCID 72720780 | 50% |
Reaction Steps
The title compound (85 mg, 0.18 mmol) was prepared from 2-(4,6-dimethylpyridin-2-yl)-2H-pyrido[2,3-e][1,2,4]thiadiazin-3(4H)-one 1,1-dioxide (IntF2) (110 mg, 0.36 mmol), 2,6-difluoro-4-methoxybenzyl bromide (103 mg, 0.43 mmol) and K2CO3 (75 mg, 0.54 mmol) in DMF (3 mL) using the methods of (115).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249160B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-c5009a8996414e058ed4ff74b825122a |
| Source note | uspto-grants-2016_02 |