Potassium Carbonate → HCID 89568606, compound

Participants

Reaction Conditions

Reaction Steps

In a stream of argon, 517 mg (0.996 mmol) of 2-[5-(anthracen-9-yl)-3-chlorophenyl]-4,6-diphenylpyrimidine, 299 mg (1.20 mmol) of 4-(quinolin-2-yl)phenylboronic acid and 4.5 mg (20 μmol) of palladium acetate and 29.6 mg (60 μmol) of 2-dicyclohexylphosphino-2′,4′,6′-triisopropylbiphenyl were suspended in a toluene (4.5 mL)/n-butanol (0.5 mL) mixed solvent, and the suspension was heated to 95° C. 800 μL (2.40 mmol) of an aqueous 3.0M potassium carbonate solution was gradually dropwise added to the mixture, and the mixture was stirred at that temperature for 2 hours. Then the reaction mixture was left to be cooled to room temperature, and water was added to the reaction mixture. Then the deposited solid was collected by filtration to give 645 mg of target 2-[5-(anthracen-9-yl)-4′-(quinoline-2-yl) biphenyl-3-yl]-4,6-diphenylpyrimidine as a white solid (yield, 94%).

Provenance & Evidence