Dichloromethane → Methyl 6-amino-5-formyl-2-methyl-4-(p-tolyl)nicotinate
Reaction equation
[Cl:33][CH2:34][Cl:35].[NH2:1][c:2]1[n:3][c:4]([CH3:21])[c:5]([C:6](=[O:7])[O:8][CH3:9])[c:10](-[c:14]2[cH:15][cH:16][c:17]([CH3:20])[cH:18][cH:19]2)[c:11]1[CH2:12][OH:13].[O:22]=[Cr:23]([Cl:24])([O-:25])=[O:26].[nH+:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1>>[NH2:1][c:2]1[n:3][c:4]([CH3:21])[c:5]([C:6](=[O:7])[O:8][CH3:9])[c:10](-[c:14]2[cH:15][cH:16][c:17]([CH3:20])[cH:18][cH:19]2)[c:11]1[CH:12]=[O:13]Participants
5
Sources & evidence
- ORD record
- ord-254af2646676445c99989df523131600
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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