HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58056219, compound → HCID 58056117, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58056219 | HCID 58056219 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 58056117 | HCID 58056117 | 39.6% |
Reaction Steps
A mixture of (E)-3-(3-amino-4-methoxy-phenyl)-prop-2-en-1-ol (250 mg) and palladium hydroxide on carbon (20%, 50 mg) in ethyl acetate (10 mL) was stirred under hydrogen atmosphere (balloon pressure) overnight. The resulting mixture was filtered over a CELITE™ pad, the filter cake was washed with dichloromethane and the filtrate was evaporated under reduced pressure to give 100 mg of 3-(3-amino-4-methoxy-phenyl)-propan-1-ol without further purifications.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09255110B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-438fcae9b363407cb4dca7c8262ab448 |
| Source note | uspto-grants-2016_02 |