HCID 58056282, compound → HCID 58056088, compound

HRID 1773585Notes

Reaction equation

HRID 1773585 reaction equation
[Cl:1][C:2]1[CH:24]=[CH:23][C:5]([O:6][CH2:7][C:8]2[O:12][C:11]([Si:13]([CH:20]([CH3:22])[CH3:21])([CH:17]([CH3:19])[CH3:18])[CH:14]([CH3:16])[CH3:15])=[N:10][CH:9]=2)=[C:4]([N+:25]([O-])=O)[CH:3]=1>[Zn]>[Cl:1][C:2]1[CH:24]=[CH:23][C:5]([O:6][CH2:7][C:8]2[O:12][C:11]([Si:13]([CH:17]([CH3:19])[CH3:18])([CH:20]([CH3:22])[CH3:21])[CH:14]([CH3:15])[CH3:16])=[N:10][CH:9]=2)=[C:4]([NH2:25])[CH:3]=1

Participants

3

Reactant 1

HCID 58056282HCID 58056282, compound

Product 1

HCID 58056088HCID 58056088, compound

Reagents, catalysts & solvents 1

HCID 23994ZincCatalyst

Procedure

5-(4-Chloro-2-nitro-phenoxymethyl)-2-triisopropylsilanyl-oxazole was reduced utilizing zinc dust as described in Preparation 20, Step B, to give 100 mg of 5-chloro-2-(2-triisopropylsilanyl-oxazol-5-ylmethoxy)-phenylamine.

Workup

  1. customas described in Preparation 20, Step B

Sources & evidence

ORD record
ord-8f02a864bc6846aeb8f86b48f6766205
Source dataset
uspto-grants-2016_02
Patent number
US09255110B2

Reaction notes

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