Cesium carbonate → HCID 86296385, compound

HRID 1773664Notes

Reaction equation

HRID 1773664 reaction equation
[C:1]1([C:7]2[C:12](B(O)O)=[CH:11][CH:10]=[CH:9][N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C([O-])([O-])=O.[Cs+].[Cs+].[CH3:22][C:23]1[C:27]([C:28]2[CH:29]=[C:30](C3C(C)=CC=C4C=3C=CC=N4)[C:31]3[NH:35][C:34](=[O:36])[NH:33][C:32]=3[CH:37]=2)=[C:26]([CH3:49])[O:25][N:24]=1>>[CH3:22][C:23]1[C:27]([C:28]2[CH:29]=[C:30]([C:12]3[C:7]([C:1]4[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=4)=[N:8][CH:9]=[CH:10][CH:11]=3)[C:31]3[NH:35][C:34](=[O:36])[NH:33][C:32]=3[CH:37]=2)=[C:26]([CH3:49])[O:25][N:24]=1

Participants

4

Reactant 3

HCID 10796Cesium carbonateHCID 27630852-Phenylpyridine-3-boronic acidHCID 86296389HCID 86296389, compound

Product 1

HCID 86296385HCID 86296385, compound

Procedure

6-(3,5-dimethylisoxazol-4-yl)-4-(2-phenylpyridin-3-yl)-1H-benzo[d]imidazol-2(3H)-one was synthesized using 2-phenylpyridin-3-ylboronic acid and Cs2CO3 in a similar fashion as 6-(3,5-dimethylisoxazol-4-yl)-4-(6-methylquinolin-5-yl)-1H-benzo[d]imidazol-2(3H)-one (Example 2).

Sources & evidence

ORD record
ord-1c7b4bb1d20940239be586852d0b8652
Source dataset
uspto-grants-2016_02
Patent number
US09255089B2

Reaction notes

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