HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Oxalate → rac-2-(1-Phenoxy-ethyl)-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Oxalate | HCID 7268 | — |
| Reactant | 3-Phenoxy-2-butanone | HCID 2764474 | — |
| Reactant | HCID 57435086 | HCID 57435086 | — |
| Reactant | ethyl 1-{2-[(tert-butoxycarbonyl)amino]propyl}-3-(phenoxymethyl)-1H-pyrazole-5-carboxylate | HCID 67958408 | — |
| Reactant | HCID 67960066 | HCID 67960066 | — |
| Reactant | Rac-6-methyl-2-phenoxymethyl-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrazine | HCID 67960219 | — |
| Reactant | HCID 178469067 | HCID 178469067 | — |
| Product | rac-2-(1-Phenoxy-ethyl)-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrazine | HCID 67968152 | — |
Reaction Steps
The compound was prepared from 3-phenoxy-butan-2-one and diethyl oxalate using the methods described in the preceding examples 9 (2,4-dioxo-5-phenoxy-pentanoic acid ethyl ester), 10 (5-phenoxymethyl-2H-pyrazole-3-carboxylic acid ethyl ester), 11 (rac-2-(2-tert-butoxycarbonylamino-propyl)-5-phenoxymethyl-2H-pyrazole-3-carboxylic acid ethyl ester), 12 (rac-6-methyl-2-phenoxymethyl-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-4-one), and 13 (rac-6-methyl-2-phenoxymethyl-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrazine).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09255103B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-8a014eecfc60427f8a544be4472d3137 |
| Source note | uspto-grants-2016_02 |