Cyanuric chloride → HCID 87242098, compound

Participants

Reaction Steps

To a cold (0° C.) solution of cyclododecanone oxime (7.89 g, 0.04 mol) in dry pyridine (30 ml) is added cyanuric chloride (1.84 g, 0.01 mol). An exothermic reaction occurs and the temperature rises to 20° C. The solution is then stirred 20 h at room temperature and then poured into 300 ml of ice-cold water. The precipitated solid is filtered off and chromatographed (silica gel, CH2Cl2—C2H5O(CO)CH3 95:5). The pure fraction is recrystallized from ethylacetate-hexane to afford 2.36 g of the title compound as a white solid, m.p. 104-107° C.

Provenance & Evidence