2-(2-Chlorophenyl)ethyl methanesulfonate → 1-[2-(2-Chlorophenyl)ethyl]-4-iodoimidazole
Reaction equation
[I:1][C:2]1[N:3]=[CH:4][NH:5][CH:6]=1.[Cl:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[CH2:14][CH2:15]OS(C)(=O)=O>>[Cl:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[CH2:14][CH2:15][N:5]1[CH:6]=[C:2]([I:1])[N:3]=[CH:4]1Participants
3
Procedure
The compound is synthesized using the method described in example 4C starting from 4-iodo-1H-imidazole and methanesulfonic acid 2-(2-chlorophenyl)-ethyl ester (example 78D).
Workup
- customThe compound is synthesized
Sources & evidence
- ORD record
- ord-d5d4ccc72c804089a7193c5022192004
- Source dataset
- uspto-grants-2016_02
- Patent number
- US09255101B2
Reaction notes
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