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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 177397Generated: October 27, 2026

Dimethylformamide → (RS)-N-(4-cyano-2-methylcarbamoylmethoxy-benzyl)-2-(2,6-difluoro-4-methoxy-phenyl)-2-methoxy-acetamide

https://huagongshe.com/reaction/177397

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantCarbonate IonHCID 19660—
Reactant2-chloro-N-methylacetamideHCID 66773—
ReactantCesium cationHCID 104967—
Reactant(RS)-N-(4-cyano-2-hydroxy-benzyl)-2-(2,6-difluoro-4-methoxy-phenyl)-2-methoxy-acetamideHCID 21905527—
Product(RS)-N-(4-cyano-2-methylcarbamoylmethoxy-benzyl)-2-(2,6-difluoro-4-methoxy-phenyl)-2-methoxy-acetamideHCID 21905466—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-1a64cb5d6e1b4e4ab1b2998e98bd239b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)