HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 89648997, compound → HCID 118353166, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 89648997 | HCID 89648997 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 118353166 | HCID 118353166 | — |
Reaction Steps
To a solution of (4-benzyloxy-3-isopropyl-phenyl)-acetic acid tert-butyl ester (3.04 g, 8.16 mmol, 1 eq) in THF (99 mL) under N2, palladium on activated carbon (10 wt. % 304 mg) was added. The flask was carefully evacuated and refilled with H2 (3×). The black suspension was stirred at r.t. under an H2-atmosphere for 2 days. The black suspension was filtered through Celite and the filter cake was rinsed with THF. The filtrate was concentrated in vacuo to give the title compound as a colorless oil. The product was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09255090B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-1418242edb504cdca618ae7c625fa5f1 |
| Source note | uspto-grants-2016_02 |