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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1773983Generated: November 2, 2026

HCID 89648997, compound → HCID 118353166, compound

https://huagongshe.com/reaction/1773983

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 89648997HCID 89648997—
CatalystPalladiumHCID 23938—
SolventTetrahydrofuranHCID 8028—
ProductHCID 118353166HCID 118353166—

Reaction Steps

To a solution of (4-benzyloxy-3-isopropyl-phenyl)-acetic acid tert-butyl ester (3.04 g, 8.16 mmol, 1 eq) in THF (99 mL) under N2, palladium on activated carbon (10 wt. % 304 mg) was added. The flask was carefully evacuated and refilled with H2 (3×). The black suspension was stirred at r.t. under an H2-atmosphere for 2 days. The black suspension was filtered through Celite and the filter cake was rinsed with THF. The filtrate was concentrated in vacuo to give the title compound as a colorless oil. The product was used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09255090B2
Source datasetuspto-grants-2016_02
ORD IDord-1418242edb504cdca618ae7c625fa5f1
Source noteuspto-grants-2016_02