4-Acetamidophenylboronic acid → HCID 24810711, compound

HRID 1774114Notes

Reaction equation

HRID 1774114 reaction equation
[NH2:1][C:2]1[N:11]=[C:10]([N:12]2[CH2:17][CH2:16][N:15]([C:18](=[O:20])[CH3:19])[CH2:14][CH2:13]2)[C:9]2[C:4](=[CH:5][CH:6]=[C:7](Br)[CH:8]=2)[N:3]=1.[C:22]([NH:25][C:26]1[CH:31]=[CH:30][C:29](B(O)O)=[CH:28][CH:27]=1)(=[O:24])[CH3:23]>>[NH2:1][C:2]1[N:11]=[C:10]([N:12]2[CH2:17][CH2:16][N:15]([C:18](=[O:20])[CH3:19])[CH2:14][CH2:13]2)[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:29]3[CH:30]=[CH:31][C:26]([NH:25][C:22](=[O:24])[CH3:23])=[CH:27][CH:28]=3)[CH:8]=2)[N:3]=1

Participants

3

Reactant 2

HCID 27346574-Acetamidophenylboronic acidHCID 24810154HCID 24810154, compound

Product 1

HCID 24810711HCID 24810711, compoundYield 91%

Procedure

This compound was synthesized from the product of example 18 and 4-acetamidophenyl-boronic acid in 91% yield, using the procedure described for example 7, and was characterized by its mass spectrum as follows: MS (m/z): 405 ([M+H]+, 100).

Sources & evidence

ORD record
ord-e9b57917ca28466e920e17d04d68bef1
Source dataset
uspto-grants-2016_02
Patent number
US09259426B2

Reaction notes

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