Butylamine → HCID 57958824, compound

HRID 1774119Notes

Reaction equation

HRID 1774119 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([C:12]3[CH:17]=[CH:16][C:15]([F:18])=[CH:14][CH:13]=3)[CH:10]=2)[N:5]=[CH:4][N:3]=1.[CH2:19]([NH2:23])[CH2:20][CH2:21][CH3:22]>>[CH2:19]([NH:23][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([C:12]3[CH:17]=[CH:16][C:15]([F:18])=[CH:14][CH:13]=3)[CH:10]=2)[N:5]=[CH:4][N:3]=1)[CH2:20][CH2:21][CH3:22]

Participants

3

Reactant 2

HCID 8007ButylamineHCID 57958802HCID 57958802, compound

Product 1

HCID 57958824HCID 57958824, compoundYield 68%

Procedure

This compound was synthesized from 4-chloro-6-(4-fluorophenyl)-quinazoline and n-butylamine in 68% yield, using the procedure described for example 37. The product was characterized by its mass spectrum as follows: MS (m/z): 296 ([M+H]+, 100).

Sources & evidence

ORD record
ord-d290dcdd88dc4afe8cb630a9e15553a0
Source dataset
uspto-grants-2016_02
Patent number
US09259426B2

Reaction notes

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