Dimethylamine → HCID 57958815, compound

HRID 1774122Notes

Reaction equation

HRID 1774122 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([C:12]3[CH:17]=[CH:16][C:15]([F:18])=[CH:14][CH:13]=3)[CH:10]=2)[N:5]=[CH:4][N:3]=1.[CH3:19][NH:20][CH3:21]>>[CH3:19][N:20]([C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([C:12]3[CH:17]=[CH:16][C:15]([F:18])=[CH:14][CH:13]=3)[CH:10]=2)[N:5]=[CH:4][N:3]=1)[CH3:21]

Participants

3

Reactant 2

HCID 674DimethylamineHCID 57958802HCID 57958802, compound

Product 1

HCID 57958815HCID 57958815, compoundYield 76%

Procedure

This compound was synthesized from 4-chloro-6-(4-fluorophenyl)-quinazoline and dimethylamine in 76% yield, using the procedure described for example 37 and was characterized by its mass spectrum as follows: MS (m/z): 268 ([M+H]+, 100).

Sources & evidence

ORD record
ord-9260e7284b924907bb994fd1c222b568
Source dataset
uspto-grants-2016_02
Patent number
US09259426B2

Reaction notes

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