Cyclopropylamine → HCID 57958820, compound

HRID 1774124Notes

Reaction equation

HRID 1774124 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([C:12]3[CH:17]=[CH:16][C:15]([F:18])=[CH:14][CH:13]=3)[CH:10]=2)[N:5]=[CH:4][N:3]=1.[CH:19]1([NH2:22])[CH2:21][CH2:20]1>>[CH:19]1([NH:22][C:2]2[C:11]3[C:6](=[CH:7][CH:8]=[C:9]([C:12]4[CH:17]=[CH:16][C:15]([F:18])=[CH:14][CH:13]=4)[CH:10]=3)[N:5]=[CH:4][N:3]=2)[CH2:21][CH2:20]1

Participants

3

Reactant 2

HCID 69828CyclopropylamineHCID 57958802HCID 57958802, compound

Product 1

HCID 57958820HCID 57958820, compoundYield 80%

Procedure

This compound was synthesized from 4-chloro-6-(4-fluorophenyl)-quinazoline and cyclopropylamine in 80% yield, using the procedure described example 37 and was characterized by its mass spectrum as follows: MS (m/z): 298 ([M+H]+, 100).

Sources & evidence

ORD record
ord-fcbe9dc9a9cd4c7790a008d1c295a1ca
Source dataset
uspto-grants-2016_02
Patent number
US09259426B2

Reaction notes

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