Potassium Phosphate, Tribasic → HCID 24768085, compound

Participants

Reaction Conditions

Reaction Steps

To a Parr hydrogenation vessel under a nitrogen atmosphere was charged 5% Pd/Al2O3 (1.02 g, 10 wt % load) and K3PO4 (6.92 g, 1.05 equiv) followed by the 1-methyl-2-pyrrolidinone solution from Example 13 (31.4 g of a 31 wt % solution, 29.9 mmol). The vessel was sealed and sparged with hydrogen and then warmed to 40° C. with shaking. After 4 hours, the vessel was sparged with nitrogen, cooled to ambient temperature and filtered. The catalyst and solids were rinsed with 1-methyl-2-pyrrolidinone (2×10 g). The crude solution was used in the next step.

Provenance & Evidence