4-Bromo-1-ethyl-1H-pyrazole → HCID 71077999, compound

HRID 1774501Notes

Reaction equation

HRID 1774501 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([S:12][C:13]2[C:21]3[C:16](=[C:17]([F:23])[C:18]([Cl:22])=[CH:19][CH:20]=3)[NH:15][C:14]=2[CH3:24])[N:7]=1)=[O:5])[CH3:2].Br[C:26]1[CH:27]=[N:28][N:29]([CH2:31][CH3:32])[CH:30]=1>>[CH2:1]([O:3][C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([S:12][C:13]2[C:21]3[C:16](=[C:17]([F:23])[C:18]([Cl:22])=[CH:19][CH:20]=3)[N:15]([C:26]3[CH:27]=[N:28][N:29]([CH2:31][CH3:32])[CH:30]=3)[C:14]=2[CH3:24])[N:7]=1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 125652014-Bromo-1-ethyl-1H-pyrazoleHCID 71078170HCID 71078170, compound

Product 1

HCID 71077999HCID 71077999, compound

Procedure

Prepared according to the procedure described in Example 9, Step 4, using the following starting materials: 6-(6-chloro-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl)-pyridine-2-carboxylic acid ethyl ester and 4-bromo-1-ethyl-1H-pyrazole.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-5ef704dd5b2449979c05d00f94b32f05
Source dataset
uspto-grants-2016_02
Patent number
US09260416B2

Reaction notes

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