4-Bromo-1-ethyl-1H-pyrazole → HCID 71078097, compound

HRID 1774510Notes

Reaction equation

HRID 1774510 reaction equation
[CH2:1]([O:3][C:4](=[O:24])[CH2:5][N:6]1[CH:10]=[C:9]([S:11][C:12]2[C:20]3[C:15](=[C:16]([F:22])[C:17]([Cl:21])=[CH:18][CH:19]=3)[NH:14][C:13]=2[CH3:23])[CH:8]=[N:7]1)[CH3:2].Br[C:26]1[CH:27]=[N:28][N:29]([CH2:31][CH3:32])[CH:30]=1>>[CH2:1]([O:3][C:4](=[O:24])[CH2:5][N:6]1[CH:10]=[C:9]([S:11][C:12]2[C:20]3[C:15](=[C:16]([F:22])[C:17]([Cl:21])=[CH:18][CH:19]=3)[N:14]([C:26]3[CH:27]=[N:28][N:29]([CH2:31][CH3:32])[CH:30]=3)[C:13]=2[CH3:23])[CH:8]=[N:7]1)[CH3:2]

Participants

3

Reactant 2

HCID 125652014-Bromo-1-ethyl-1H-pyrazoleHCID 71078006HCID 71078006, compound

Product 1

HCID 71078097HCID 71078097, compound

Procedure

Prepared according to the procedure described in Example 9, Step 4, using the following starting materials: [4-(6-chloro-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl)-pyrazol-1-yl]-acetic acid ethyl ester and 4-bromo-1-ethyl-1H-pyrazole.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-8f22201ea2f741bcae66027c2efaceab
Source dataset
uspto-grants-2016_02
Patent number
US09260416B2

Reaction notes

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