4-Methoxy-alpha-toluenethiol → [6-(4-Methoxy-benzylsulfanyl)-pyridin-2-yl]-acetic acid ethyl ester

HRID 1774511Notes

Reaction equation

HRID 1774511 reaction equation
[CH2:1]([O:3][C:4](=[O:13])[CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8](Br)[N:7]=1)[CH3:2].[CH3:14][O:15][C:16]1[CH:23]=[CH:22][C:19]([CH2:20][SH:21])=[CH:18][CH:17]=1>>[CH2:1]([O:3][C:4](=[O:13])[CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([S:21][CH2:20][C:19]2[CH:22]=[CH:23][C:16]([O:15][CH3:14])=[CH:17][CH:18]=2)[N:7]=1)[CH3:2]

Participants

3

Reactant 2

HCID 804074-Methoxy-alpha-toluenethiolHCID 53419420Ethyl 2-(6-bromopyridin-2-yl)acetate

Product 1

HCID 71076568[6-(4-Methoxy-benzylsulfanyl)-pyridin-2-yl]-acetic acid ethyl ester

Procedure

Prepared according to the procedure described in Example 16, Step 2, using the following starting materials: (6-bromo-pyridin-2-yl)-acetic acid ethyl ester and 4-methoxybenzyl mercaptan.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-b2119ba152f641be8cb6f3be4b055de2
Source dataset
uspto-grants-2016_02
Patent number
US09260416B2

Reaction notes

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