4-Bromo-1-propyl-1H-pyrazole → HCID 71078125, compound

HRID 1774515Notes

Reaction equation

HRID 1774515 reaction equation
[CH2:1]([O:3][C:4](=[O:25])[CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([S:12][C:13]2[C:21]3[C:16](=[C:17]([F:23])[C:18]([Cl:22])=[CH:19][CH:20]=3)[NH:15][C:14]=2[CH3:24])[N:7]=1)[CH3:2].Br[C:27]1[CH:28]=[N:29][N:30]([CH2:32][CH2:33][CH3:34])[CH:31]=1>>[CH2:1]([O:3][C:4](=[O:25])[CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([S:12][C:13]2[C:21]3[C:16](=[C:17]([F:23])[C:18]([Cl:22])=[CH:19][CH:20]=3)[N:15]([C:27]3[CH:28]=[N:29][N:30]([CH2:32][CH2:33][CH3:34])[CH:31]=3)[C:14]=2[CH3:24])[N:7]=1)[CH3:2]

Participants

3

Reactant 2

HCID 218597074-Bromo-1-propyl-1H-pyrazoleHCID 71078091HCID 71078091, compound

Product 1

HCID 71078125HCID 71078125, compound

Procedure

Prepared according to the procedure described in Example 9, Step 4, using the following starting materials: [6-(6-chloro-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl)-pyridin-2-yl]-acetic acid ethyl ester and 4-bromo-1-propyl-1H-pyrazole.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-62097dabf3024f68833d5c87a8af7f6b
Source dataset
uspto-grants-2016_02
Patent number
US09260416B2

Reaction notes

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