HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 67328992, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 2,6-Lutidine | HCID 7937 | — |
| Reactant | Hydrazine | HCID 9321 | — |
| Reactant | HCID 4935696 | HCID 4935696 | — |
| Product | HCID 67328992 | HCID 67328992 | — |
Reaction Steps
Compound 47 is prepared from methyl 4-(benzyloxycarbonylamino)benzoate (45) and compound 46 under basic condition (e.g. 2-6-lutidine or pyridine). The ester functional group of compound 47 is then converted to hydrazide first (with hydrazine) and then Cbz protecting group is deprotected under hydrogenation condition to afford compound 48.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09260417B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-81f5892ecbea47b9abfe889e7418e890 |
| Source note | uspto-grants-2016_02 |