HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphenylphosphine → HCID 178454069, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | 3-Bromo-5-hydroxypyridine | HCID 599529 | — |
| Reactant | (4-chlorophenyl)methyl (NZ)-N-[(4-chlorophenyl)methoxycarbonylimino]carbamate | HCID 16218364 | — |
| Reactant | HCID 178418813 | HCID 178418813 | — |
| Product | HCID 178454069 | HCID 178454069 | — |
Reaction Steps
In analogy to the procedure described for the preparation of intermediate A-7, 5-bromopyridin-3-ol was reacted with (cis)-(4-hydroxy-cyclohexyl)-carbamic acid tert-butyl ester in presence of di-(4-chlorobenzyl)azodicarboxylate and triphenylphosphine to give the title compound as a colorless solid. MS: 371.3 and 373.3 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09260408B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-a56f300e5dd647e7ad7f20302ae2bd49 |
| Source note | uspto-grants-2016_02 |