HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloropyridine-2-carboxylic acid → N-((5-Bromopyridin-3-yl)methyl)-3-chloropicolinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloropyridine-2-carboxylic acid | HCID 824632 | — |
| Reactant | 3-(Aminomethyl)-5-bromopyridine | HCID 22992264 | — |
| Product | N-((5-Bromopyridin-3-yl)methyl)-3-chloropicolinamide | HCID 86679147 | — |
Reaction Steps
In analogy to the procedure described for the preparation of example 75, coupling of (5-bromopyridin-3-yl)methanamine with 3-chloro-pyridine-2-carboxylic acid gave the title compound as off-white solid. MS: 326.2 and 328.2 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09260408B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-7c37a80578ac4551b3dc786875f5f392 |
| Source note | uspto-grants-2016_02 |