HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Pyridinylboronic acid → 6-Pyridin-3-yl-3,4-dihydro-1H-[1,5]naphthyridin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Pyridinylboronic acid | HCID 2734378 | — |
| Reactant | 3-(6-Bromo-3-nitro-pyridin-2-yl)-3-(toluene-4-sulfonyl)-propionic acid methyl ester | HCID 86679157 | — |
| Product | 6-Pyridin-3-yl-3,4-dihydro-1H-[1,5]naphthyridin-2-one | HCID 71533449 | — |
Reaction Steps
In analogy to the procedures described for the preparation of example 32 (steps [C] to [D]), the title compound was prepared using 3-(6-bromo-3-nitro-pyridin-2-yl)-3-(toluene-4-sulfonyl)-propionic acid methyl ester and 3-pyridine boronic acid as corresponding starting materials. MS: 226.1 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09260408B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-c0b59bad6af34ea799db5ce8e0aefd33 |
| Source note | uspto-grants-2016_02 |