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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1774806Generated: November 2, 2026

Cyclopropanecarboxylic acid → Cyclopropanecarboxylic acid [5-(1-methyl-2-oxo-1,2,3,4-tetrahydro-quinolin-6-yl)-pyridin-3-ylmethyl]-amide

https://huagongshe.com/reaction/1774806

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanecarboxylic acidHCID 15655—
Reactant6-(5-Aminomethyl-pyridin-3-yl)-1-methyl-3,4-dihydro-1H-quinolin-2-oneHCID 71533452—
ProductCyclopropanecarboxylic acid [5-(1-methyl-2-oxo-1,2,3,4-tetrahydro-quinolin-6-yl)-pyridin-3-ylmethyl]-amideHCID 71533503—

Reaction Steps

In analogy to the procedure described for the preparation of example 37, 6-(5-aminomethyl-pyridin-3-yl)-1-methyl-3,4-dihydro-1H-quinolin-2-one (example 36) has been reacted with cyclopropanecarboxylic acid to give the title compound as a white solid. MS: 336.3 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09260408B2
Source datasetuspto-grants-2016_02
ORD IDord-630d325a59214222b798133bb6250ef0
Source noteuspto-grants-2016_02