3-Chloropyridine-2-carboxylic acid → 3-Chloro-pyridine-2-carboxylic acid {2-[5-(1-methyl-2-oxo-1,2,3,4-tetrahydro-quinolin-6-yl)-pyridin-3-yloxy]-ethyl}-amide

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Reaction Steps

In analogy to the procedure described for the preparation of example 75, 6-[5-(2-amino-ethoxy)-pyridin-3-yl]-1-methyl-3,4-dihydro-1H-quinolin-2-one hydrochloride (example 42) has been coupled with 3-chloro-pyridine-2-carboxylic acid to give the title compound as a light yellow viscous oil. MS: 437.4 (M+H+).

Provenance & Evidence