Bis(pinacolato)diborane → HCID 86679220, compound

Participants

Reaction Steps

In analogy to the procedure described for the preparation of example 45, 9-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,6,7-tetrahydropyrido[3,2,1-ij]quinolin-3(5H)-one (prepared from 9-bromo-1,2,6,7-tetrahydropyrido[3,2,1-ij]quinolin-3(51H)-one and 4,4,4′,4′,5,5,5′,5′-octamethyl-2,2′-bi(1,3,2-dioxaborolane) in analogy to the procedure described for the preparation of intermediate A-1 [B]) has been coupled to ethanesulfonic acid (5-bromo-pyridin-3-ylmethyl)-amide (intermediate A-11) to give the title compound as an off-white amorphous solid. MS: 386.2 (M+H+).

Provenance & Evidence