Hydrochloric Acid → 6-[5-(2-Amino-ethoxy)-pyridin-3-yl]-7-fluoro-1-methyl-3,4-dihydro-1H-quinolin-2-one hydrochloride

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Reaction Steps

In analogy to the procedure described for the preparation of example 42, reaction of {2-[5-(7-fluoro-1-methyl-2-oxo-1,2,3,4-tetrahydro-quinolin-6-yl)-pyridin-3-yloxy]-ethyl}-carbamic acid tert-butyl ester (example 232) with hydrogen chloride (in dixoane) in methanol gave the title compound as light yellow solid. MS: 316.5 (M+H+).

Provenance & Evidence