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HRID1774906

反应详情

EQUATION

反应方程式

HRID 1774906 的结构方程式

REACTANTS

反应物

2
结构：O=c1c2cc(Cc3ccc(Cl)nc3)c3ccccc3c2ncn1[C@H]1CCOC[C@@H]1O
HCID51000617

未命名化合物

结构：Clc1ccc(C[Zn+])cn1.[Cl-]
HCID178478124

未命名化合物

PRODUCTS

生成物

1
结构：O=c1c2cc(Cc3ccc(Cl)cc3)c3ccccc3c2ncn1[C@H]1CCOC[C@@H]1O
HCID67970490

未命名化合物

PROCEDURE

实验过程

6-(4-Chlorobenzyl)-3-[(3R,4S)-3-hydroxytetrahydro-2H-pyran-4-yl]benzo[h]quinazolin-4(3H)-one was prepared by the procedure described for the synthesis of 6-[(6-chloropyridin-3-yl)methyl]-3-[(3R,4S)-3-hydroxytetrahydro-2H-pyran-4-yl]benzo[h]quinazolin-4(3H)-one in Example 1, substituting 4-chlorobenzylzinc chloride for (2-chloro-5-pyridyl)methylzinc chloride.