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HRID1775094

反应详情

EQUATION

反应方程式

HRID 1775094 的结构方程式

REACTANTS

反应物

2
结构：Cl.O[C@@H]1CCNC1
HCID2759336

(R)-3-Hydroxypyrrolidine hydrochloride

C4H10ClNO

结构：C[Si](C)(C)CCOCn1nc(-c2ccc(Br)c(F)n2)c2cc(-c3cccnc3)ncc21
HCID71253450

未命名化合物

PRODUCTS

生成物

1
结构：O[C@@H]1CCN(c2nc(-c3n[nH]c4cnc(-c5cccnc5)cc34)ccc2Br)C1
HCID71253352

未命名化合物

收率 9.6%

PROCEDURE

实验过程

Following the procedures as described in Example 241 and starting with 3-(5-bromo-6-fluoropyridin-2-yl)-5-(pyridin-3-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazolo[3,4-c]pyridine and (R)-pyrrolidin-3-ol hydrochloride, 293 was obtained as an off-white solid (3.50 mg, 9.60%) over two steps. ESI MS m/z=437.1 (M+1)