Methyl iodide → HCID 71626392, compound

HRID 1775203Notes

Reaction equation

HRID 1775203 reaction equation
[CH3:1][C:2]1([CH3:20])[CH2:14][C:13](=O)[C:12]2[C:11]3[C:10]([C:16](OC)=[O:17])=[CH:9][CH:8]=[CH:7][C:6]=3[NH:5][C:4]=2[CH2:3]1.[CH3:21]I.CN1C2CCCC3=[N:37][NH:38]C(=O)C4C(C=23)=C1C=CC=4>>[CH3:1][C:2]1([CH3:20])[CH2:14][C:13]2=[N:37][NH:38][C:16](=[O:17])[C:10]3[C:11]4[C:12]2=[C:4]([N:5]([CH3:21])[C:6]=4[CH:7]=[CH:8][CH:9]=3)[CH2:3]1

Participants

4

Reactant 3

HCID 6328Methyl iodideHCID 71626391HCID 71626391, compoundHCID 89657302HCID 89657302, compound

Product 1

HCID 71626392HCID 71626392, compound

Procedure

Compound 23 was prepared from methyl 2,2-dimethyl-4-oxo-2,3,4,9-tetrahydro-1H-carbazole-5-carboxylate and methyl iodide according to the procedures for Compound 22 under appropriate conditions recognized by one of ordinary skill in the art. 1H NMR (DMSO-d6) δ 9.86 (s, 1H), 7.42-7.53 (m, 2H), 7.12 (t, 1H, J=7.8 Hz), 3.66 (s, 3H), 2.67 (s, 2H), 2.20 (s, 2H), and 1.04 (s, 6H). MS (ESI) m/e [M+1]+ 268.

Sources & evidence

ORD record
ord-eb92c233e02049408cc5a3a6ecde9db3
Source dataset
uspto-grants-2016_02
Patent number
US09260440B2

Reaction notes

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