HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylmethyl 3,5-dioxo-1-piperidinecarboxylate → HCID 136242925, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylmethyl 3,5-dioxo-1-piperidinecarboxylate | HCID 49761164 | — |
| Reactant | methyl 3-amino-2-bromo-5-fluorobenzoate | HCID 63022281 | — |
| Reactant | HCID 136242914 | HCID 136242914 | — |
| Product | HCID 136242925 | HCID 136242925 | — |
Reaction Steps
Compound 57 was prepared from methyl 2-bromo-5-fluoro-3-aminobenzoate and benzyl 3,5-dioxopiperidine-1-carboxylate according to the procedures similar to those for Compound 44. 1H NMR (DMSO-d6) δ 11.8 (s, 1H), 10.1 (s, 1H), 7.36 (dd, 1H, J=1.8, 9.0 Hz), 7.19 (dd, 1H, J=1.8, 10.2 Hz), 3.80 (s, 2H), 3.30 (s, 2H), 2.50-2.54 (m, 2H), 1.50-1.54 (m, 2H), and 0.89 (t, 3H, J=7.8 Hz). MS (ESI) m/e [M+1]+ 287.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09260440B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-f888fe306ba54387a84b1210cbe6da6e |
| Source note | uspto-grants-2016_02 |