HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylmethyl 3,5-dioxo-1-piperidinecarboxylate → HCID 136242926, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylmethyl 3,5-dioxo-1-piperidinecarboxylate | HCID 49761164 | — |
| Reactant | methyl 3-amino-2-bromo-5-fluorobenzoate | HCID 63022281 | — |
| Reactant | HCID 136242914 | HCID 136242914 | — |
| Product | HCID 136242926 | HCID 136242926 | — |
Reaction Steps
Compound 58 was prepared from methyl 2-bromo-5-fluoro-3-aminobenzoate and benzyl 3,5-dioxopiperidine-1-carboxylate according to the procedures similar to those for Compound 44. 1H NMR (DMSO-d6). δ 11.8 (s, 1H), 10.1 (s, 1H), 7.35 (dd, 1H, J=2.4, 9.6 Hz), 7.19 (dd, 1H, J=2.4, 10.2 Hz), 3.80 (s, 2H), 3.30 (s, 2H), 2.60-2.64 (m, 2H), and 1.09 (t, 3H, J=7.2 Hz). MS (ESI) m/e [M+1]+ 273.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09260440B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-3f416f59fc5c457abf34f85a999cd8fa |
| Source note | uspto-grants-2016_02 |