HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylmethyl 3,5-dioxo-1-piperidinecarboxylate → HCID 136242929, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylmethyl 3,5-dioxo-1-piperidinecarboxylate | HCID 49761164 | — |
| Reactant | methyl 3-amino-2-bromo-5-fluorobenzoate | HCID 63022281 | — |
| Reactant | HCID 136242928 | HCID 136242928 | — |
| Product | HCID 136242929 | HCID 136242929 | — |
Reaction Steps
Compound 61 was prepared from methyl 2-bromo-5-fluoro-3-aminobenzoate and benzyl 3,5-dioxopiperidine-1-carboxylate according to the procedures similar to those for Compound 60. 1H NMR δ 10.1 (s, 1H), 7.58 (dd, 1H, J=1.8, 10.2 Hz), 7.21 (dd, 1H, J=1.8, 10.2 Hz), 4.20-4.22 (m, 2H), 4.03 (s, 2H), 3.42 (s, 2H), 2.51-2.54 (m, 2H), and 2.19 (s, 6H). MS (ESI) m/e [M+1]+316.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09260440B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-2b06822ef8544c8da563374462272670 |
| Source note | uspto-grants-2016_02 |