Dichloromethane → 2-Fluoro-5-(6-isopropylquinolin-8-yl)-benzaldehyde

HRID 177524Notes

Reaction equation

HRID 177524 reaction equation
[Cl:23][CH2:24][Cl:25].[F:1][c:2]1[c:3]([CH2:21][OH:22])[cH:4][c:5](-[c:8]2[cH:9][c:10]([CH:18]([CH3:19])[CH3:20])[cH:11][c:12]3[cH:13][cH:14][cH:15][n:16][c:17]23)[cH:6][cH:7]1.[O:26]=[Mn:27]=[O:28]>>[F:1][c:2]1[c:3]([CH:21]=[O:22])[cH:4][c:5](-[c:8]2[cH:9][c:10]([CH:18]([CH3:19])[CH3:20])[cH:11][c:12]3[cH:13][cH:14][cH:15][n:16][c:17]23)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 14801Manganese dioxideHCID 22350104[2-Fluoro-5-(6-isopropyl-quinolin-8-yl)-phenyl]-methanol

Product 1

HCID 223500542-Fluoro-5-(6-isopropylquinolin-8-yl)-benzaldehyde

Sources & evidence

ORD record
ord-548e9d2d0437439a985e152415fa8ce7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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