HCID 102189385, compound → HCID 118193073, compound

HRID 1775421Notes

Reaction equation

HRID 1775421 reaction equation
C1(SC2C3C=CC=CC=3SC=2I)C=CC=CC=1.[N+:18]([C:21]1[CH:26]=[CH:25][C:24]([S:27][C:28]2[C:29]3[CH:37]=[CH:36][CH:35]=[CH:34][C:30]=3[S:31][C:32]=2I)=[CH:23][CH:22]=1)([O-:20])=[O:19]>>[N+:18]([C:21]1[CH:26]=[CH:25][C:24]2[S:27][C:28]3[C:29]4[CH:37]=[CH:36][CH:35]=[CH:34][C:30]=4[S:31][C:32]=3[C:23]=2[CH:22]=1)([O-:20])=[O:19]

Participants

3

Reactant 2

HCID 102189385HCID 102189385, compoundHCID 118193054HCID 118193054, compound

Product 1

HCID 118193073HCID 118193073, compoundYield 81%

Procedure

Except that 3-(phenylsulfenyl)-2-iodobenzo[b]thiophene was replaced with 3-((p-nitrophenyl)sulfenyl)-2-iodobenzo[b]thiophene, the reaction was implemented in the same way as in Example 3. Purification was implemented by column chromatography (silica gel, CHCl3, Rf: 0.9), so that a yellow solid was produced (yield: 81%).

Workup

  1. customPurification
  2. customwas produced (yield: 81%)

Sources & evidence

ORD record
ord-fb68975cdefa423599cd781236c3cb4e
Source dataset
uspto-grants-2016_02
Patent number
US09260451B2

Reaction notes

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