HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1'-Carbonyldiimidazole → hexahydroimidazo[1,5-a]pyridin-3(2H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | Piperidine-2-methylamine | HCID 90865 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | hexahydroimidazo[1,5-a]pyridin-3(2H)-one | HCID 47002315 | — |
Reaction Steps
A solution of CDI (830 mg, 5.1 mmol) and piperidin-2-ylmethanamine (520 mg, 4.6 mmol) in DCM (20 mL) was stirred at room temperature overnight. After the solvent was removed, the residue was directly used for the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09260452B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-619ee6518b044e9c8f2128490bba4c10 |
| Source note | uspto-grants-2016_02 |