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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1775516Generated: October 26, 2026

3-(3-Chlorophenyl)-3-oxopropanenitrile → 4-chloro-3-(3-chlorophenyl)-1-methyl-5-phenyl-1H-pyrazolo[3,4-c]pyridazine

https://huagongshe.com/reaction/1775516

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(3-Chlorophenyl)-3-oxopropanenitrileHCID 140855—
Reactant4-chloro-3-(2-chlorophenyl)-1-methyl-5-phenyl-1H-pyrazolo[3,4-c]pyridazineHCID 66576482—
Product4-chloro-3-(3-chlorophenyl)-1-methyl-5-phenyl-1H-pyrazolo[3,4-c]pyridazineHCID 66576558—

Reaction Steps

Compound 13 was synthesised following similar procedures outlined in Example 1 (Compound 37), using 3-chlorobenzoylacetonitrile instead of 2-chlorobenzoyl acetonitrile in Step 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09260381B2
Source datasetuspto-grants-2016_02
ORD IDord-d4ac013b68b7420da8450309614bcf93
Source noteuspto-grants-2016_02