4-Methylbenzaldehyde → HCID 66576886, compound

HRID 1775536Notes

Reaction equation

HRID 1775536 reaction equation
[Cl:1][C:2]1[C:7]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[N:6][N:5]=[C:4]2[N:14]([CH3:24])[N:15]=[C:16]([C:17]3[CH:18]=[C:19](C)[CH:20]=[CH:21][CH:22]=3)[C:3]=12.[CH3:25]C1C=CC(C=O)=CC=1>>[Cl:1][C:2]1[C:7]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[N:6][N:5]=[C:4]2[N:14]([CH3:24])[N:15]=[C:16]([C:17]3[CH:22]=[CH:21][C:20]([CH3:25])=[CH:19][CH:18]=3)[C:3]=12

Participants

3

Reactant 2

HCID 77254-MethylbenzaldehydeHCID 66576808HCID 66576808, compound

Product 1

HCID 66576886HCID 66576886, compound

Procedure

Compound 21 was synthesised following similar procedures outlined in Example 24 (Compound 19), using 4-methylbenzaldehyde instead of 3-methylbenzaldehyde in Step 1. As a slightly modified procedure, Step 3 was performed at 70° C. for 16 h in a sealed tube.

Sources & evidence

ORD record
ord-d052462fe5b548bfa048a26e53768ede
Source dataset
uspto-grants-2016_02
Patent number
US09260381B2

Reaction notes

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