HCID 66576638, compound → HCID 66576970, compound

HRID 1775546Notes

Reaction equation

HRID 1775546 reaction equation
ClC1C(C2C=CC=CC=2)=N[N:5]=[C:4]2N(C)N=C(C3C=CC(C#N)=CC=3)C=12.[Cl:26][C:27]1[C:32]([C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)=[N:31][N:30]=[C:29]2[N:39]([CH3:49])[N:40]=[C:41]([C:42]3[CH:47]=[CH:46][CH:45]=[C:44](I)[CH:43]=3)[C:28]=12.ClC1C(C2C=CC=CC=2)=NN=C2N(C)N=C(C3C=CC(I)=CC=3)C=12>>[Cl:26][C:27]1[C:32]([C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)=[N:31][N:30]=[C:29]2[N:39]([CH3:49])[N:40]=[C:41]([C:42]3[CH:43]=[C:44]([CH:45]=[CH:46][CH:47]=3)[C:4]#[N:5])[C:28]=12

Participants

4

Reactant 3

HCID 66576638HCID 66576638, compound2×HCID 66576644HCID 66576644, compound2×HCID 66576889HCID 66576889, compound

Product 1

HCID 66576970HCID 66576970, compound

Procedure

Compound 34 was synthesised following similar procedures outlined in Example 35 (Compound 24), using 4-chloro-3-(3-iodophenyl)-1-methyl-5-phenyl-1H-pyrazolo[3,4-c]pyridazine (Compound 3, Example 30) as the starting material instead of 4-chloro-3-(4-iodophenyl)-1-methyl-5-phenyl-1H-pyrazolo[3,4-c]pyridazine (Compound 43, Example 23).

Sources & evidence

ORD record
ord-b16586239aca4569b1b5a606373a70a1
Source dataset
uspto-grants-2016_02
Patent number
US09260381B2

Reaction notes

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