HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Dimethylaniline → HCID 78320483, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Dimethylaniline | HCID 7248 | — |
| Reactant | Ethyl orthoformate | HCID 31214 | — |
| Reactant | Methyl 3-amino-4-phenylthiophene-2-carboxylate | HCID 2759782 | — |
| Reactant | 3,7-Diphenylthieno[3,2-d]pyrimidin-4(3H)-one | HCID 78324865 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 78320483 | HCID 78320483 | 50% |
Reaction Steps
In the same manner as the synthesis of Compound 1, methyl 3-amino-4-phenylthiophene-2-carboxylate (70 mg, 0.30 mmol), triethyl orthoformate (0.57 ml), 3,4-dimethylaniline (67.8 mg, 0.56 mmol), and acetic acid (0.07 ml) were used to give 49.2 mg (0.15 mmol, 50% yield) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09260448B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-bc8aee14ca774e89b4c6950b1b0c31ce |
| Source note | uspto-grants-2016_02 |