HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitroaniline → HCID 78320801, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitroaniline | HCID 7475 | — |
| Reactant | Ethyl orthoformate | HCID 31214 | — |
| Reactant | Methyl 3-amino-4-phenylthiophene-2-carboxylate | HCID 2759782 | — |
| Reactant | 3,7-Diphenylthieno[3,2-d]pyrimidin-4(3H)-one | HCID 78324865 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 78320801 | HCID 78320801 | 10% |
Reaction Steps
In the same manner as the synthesis of Compound 1, methyl 3-amino-4-phenylthiophene-2-carboxylate (200 mg, 0.86 mmol), triethyl orthoformate (2 ml), 4-nitroaniline (225 mg, 1.63 mmol), and acetic acid (0.2 ml) were used to give 31 mg (0.089 mmol, 10% yield) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09260448B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-0837bde30f5246fd8f3be04d21511714 |
| Source note | uspto-grants-2016_02 |