HuagongsheHuagongshe Chemistry Print Report · For research reference only
P-Anisidine → HCID 78321115, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | P-Anisidine | HCID 7732 | — |
| Reactant | Ethyl orthoformate | HCID 31214 | — |
| Reactant | 1325307-27-4 | HCID 53335886 | — |
| Reactant | 3,7-Diphenylthieno[3,2-d]pyrimidin-4(3H)-one | HCID 78324865 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 78321115 | HCID 78321115 | 16% |
Reaction Steps
In the same manner as the synthesis of Compound 1, methyl 3-amino-4-(2-fluorophenyl)thiophene-2-carboxylate (100 mg, 0.40 mmol), triethyl orthoformate (2.0 ml), p-anisidine (91.17 mg, 0.74 mmol), and acetic acid (0.1 ml) were used to give 22 mg (0.062 mmol, 16% yield) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09260448B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-189b5fa6c5ea4c819f40a7de564bfde9 |
| Source note | uspto-grants-2016_02 |