HuagongsheHuagongshe Chemistry Print Report · For research reference only
P-Anisidine → HCID 78321754, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | P-Anisidine | HCID 7732 | — |
| Reactant | Ethyl orthoformate | HCID 31214 | — |
| Reactant | 3,7-Diphenylthieno[3,2-d]pyrimidin-4(3H)-one | HCID 78324865 | — |
| Reactant | HCID 86729803 | HCID 86729803 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 78321754 | HCID 78321754 | 23% |
Reaction Steps
In the same manner as the synthesis of Compound 1, methyl 3-amino-4-(2-bromophenyl)thiophene-2-carboxylate (1.4 g, 4.48 mmol), triethyl orthoformate (12 ml), p-anisidine (930 mg, 8.52 mmol), and acetic acid (1.2 ml) were used to give 422 mg (1.02 mmol, 23% yield) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09260448B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-9654f3e226cc481589da59937c96d243 |
| Source note | uspto-grants-2016_02 |