HuagongsheHuagongshe Chemistry Print Report · For research reference only
P-Anisidine → HCID 78322060, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | P-Anisidine | HCID 7732 | — |
| Reactant | Ethyl orthoformate | HCID 31214 | — |
| Reactant | 3,7-Diphenylthieno[3,2-d]pyrimidin-4(3H)-one | HCID 78324865 | — |
| Reactant | HCID 86729805 | HCID 86729805 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 78322060 | HCID 78322060 | 60% |
Reaction Steps
In the same manner as the synthesis of Compound 1, methyl 3-amino-4-(o -tolyl)thiophene-2-carboxylate (100 mg, 0.4 mmol), triethyl orthoformate (0.88 ml), p-anisidine (92.6 mg, 0.75 mmol), and acetic acid (0.13 ml) were used to give 83.2 mg (0.24 mmol, 60% yield) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09260448B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-21d0fe341f314297af1d0a9ea7380cf3 |
| Source note | uspto-grants-2016_02 |